dna16sam.hpp

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// -----------------------------------------------------------------------------------------------------
// Copyright (c) 2006-2022, Knut Reinert & Freie Universität Berlin
// Copyright (c) 2016-2022, Knut Reinert & MPI für molekulare Genetik
// This file may be used, modified and/or redistributed under the terms of the 3-clause BSD-License
// shipped with this file and also available at: https://github.com/seqan/seqan3/blob/master/LICENSE.md
// -----------------------------------------------------------------------------------------------------
 
#pragma once
 
#include <seqan3/alphabet/nucleotide/nucleotide_base.hpp>
 
namespace seqan3
{
 
class dna16sam : public nucleotide_base<dna16sam, 16>
{
private:
    using base_t = nucleotide_base<dna16sam, 16>;
 
    friend base_t;
    friend base_t::base_t;
 
public:
    constexpr dna16sam() noexcept = default;                             
    constexpr dna16sam(dna16sam const &) noexcept = default;             
    constexpr dna16sam(dna16sam &&) noexcept = default;                  
    constexpr dna16sam & operator=(dna16sam const &) noexcept = default; 
    constexpr dna16sam & operator=(dna16sam &&) noexcept = default;      
    ~dna16sam() noexcept = default;                                      
 
    using base_t::base_t;
 
private:
    static constexpr char_type rank_to_char_table
        [alphabet_size]{'=', 'A', 'C', 'M', 'G', 'R', 'S', 'V', 'T', 'W', 'Y', 'H', 'K', 'D', 'B', 'N'};
 
    static constexpr std::array<rank_type, 256> char_to_rank_table{[]() constexpr {std::array<rank_type, 256> ret{};
 
    // initialize with UNKNOWN (std::array::fill unfortunately not constexpr)
    for (auto & c : ret)
        c = 15; // rank of 'N'
 
    // reverse mapping for characters and their lowercase
    for (size_t rnk = 0u; rnk < alphabet_size; ++rnk)
    {
        ret[rank_to_char_table[rnk]] = rnk;
        ret[to_lower(rank_to_char_table[rnk])] = rnk;
    }
 
    // set U equal to T
    ret['U'] = ret['T'];
    ret['u'] = ret['t'];
 
    return ret;
}()
}; // namespace seqan3
 
static constexpr rank_type rank_complement_table[alphabet_size]{
    15, // N is complement of '='_dna16sam  0
    8,  // T is complement of 'A'_dna16sam  1
    4,  // G is complement of 'C'_dna16sam  2
    12, // K is complement of 'M'_dna16sam  3
    2,  // C is complement of 'G'_dna16sam  4
    10, // Y is complement of 'R'_dna16sam  5
    6,  // S is complement of 'S'_dna16sam  6
    14, // B is complement of 'V'_dna16sam  7
    1,  // A is complement of 'T'_dna16sam  8
    9,  // W is complement of 'W'_dna16sam  9
    5,  // R is complement of 'Y'_dna16sam 10
    13, // D is complement of 'H'_dna16sam 11
    3,  // M is complement of 'K'_dna16sam 12
    11, // H is complement of 'D'_dna16sam 13
    7,  // V is complement of 'B'_dna16sam 14
    15  // N is complement of 'N'_dna16sam 15
};
 
static constexpr rank_type rank_complement(rank_type const rank)
{
    return rank_complement_table[rank];
}
 
static constexpr char_type rank_to_char(rank_type const rank)
{
    return rank_to_char_table[rank];
}
 
static constexpr rank_type char_to_rank(char_type const chr)
{
    using index_t = std::make_unsigned_t<char_type>;
    return char_to_rank_table[static_cast<index_t>(chr)];
}
}
;
 
// ------------------------------------------------------------------
// containers
// ------------------------------------------------------------------
 
using dna16sam_vector = std::vector<dna16sam>;
 
// ------------------------------------------------------------------
// literals
// ------------------------------------------------------------------
inline namespace literals
{
 
constexpr dna16sam operator""_dna16sam(char const c) noexcept
{
    return dna16sam{}.assign_char(c);
}
 
inline dna16sam_vector operator""_dna16sam(char const * s, size_t n)
{
    dna16sam_vector r;
    r.resize(n);
 
    for (size_t i = 0; i < n; ++i)
        r[i].assign_char(s[i]);
 
    return r;
}
 
} // namespace literals
 
} // namespace seqan3